Reservoir dry powder inhaler

ICOresTM is a reservoir multi-dose dry powder inhaler based on a novel proprietary technology, patents pending.

ICOres can be customized to have features and handling regulatory equivalent to branded reservoir inhalers on the market. ICOres is designed to be robust and is easy to manufacture and assemble in a high volume fully automated process. ICOres is fully injection molded and available for licensing.

ICOres Features

  • Inhalation flow driven multi-dose reservoir dry powder inhaler
  • Micronized spheronized formulation or carrier based formulation
  • Dual reservoirs. Two different drug formulations or the same formulation in both reservoirs
  • Dose metering using proven and well-established scrape filling principle
  • Spheronized formulation 60-180 doses @
    1-3 mg
  • Carrier based formulation 60-180 doses @
    10-20 mg
  • A screw-on cover providing an air tight seal against ambient air
  • Integrated desiccant to provide long in-use and shelf-life stability. No need for Al pouch
  • Deaggregation options to match an originator or for optimized performance
  • Four user operations: Remove cover – Load – Inhale – Replace cover
  • Exact dose counter showing each individual dose
  • Visual feedback when loading the dose and when inhaling the dose
  • No risk of multiple dosing by design
  • Suitable for flows between 30 and 90 l/min
  • Anatomical mouthpiece
  • Hygienic and easy to clean
  • Factory filling using conventional equipment
  • Designed for fully automated assembly and low cost manufacturing


  • Low cost dry powder inhaler with 200-400 doses. Indicator instead of counter and no feedback
  • Electronic counter and feedback. Flow monitor and connectivity

Two reservoirs for combination products with two, three or even four different API

ICOres has a unique feature of having two separate reservoirs. When rotating the grip, two doses are metered into two separate cavities in the dosing disk. These two doses are then inhaled simultaneously and mixed upon exiting the inhaler. The two reservoirs can be filled with the same dry powder formulations or with two different formulations. Using two different combination formulations allows for the simultaneous delivery up to four different API.


A key decision when developing a new inhalation product is the selection between a micronized spheronized formulation or a carrier-based formulation. A spheronized formulation is more advanced and performs better in terms of fine particle fraction. Carrier-based formulations are more commonly used for inhalation products since they are inherently more robust and use conventional manufacturing equipment. ICOres comes in two different versions; one for carrier-based formulations and one for spheronized formulations.

ICOres can be designed to be bioequivalent to other dry powder inhaler products on the market. ICOres is designed to be equivalent in terms of device and performance both in vitro and in vivo.

An ICOres product can also be optimized to give optimal product performance for a given drug formulation. This option is suitable for NCEs or other products not intended to be registered as generic drugs.

Exact counter

It is very important that the user always knows how many doses are remaining in the inhaler. ICOres has a clear and accurate dose counter showing the exact number of doses. After each dose taken, the counter counts down. After taking the last dose a red bar appears in the window indicating that the inhaler is empty.

User feedback

A major concern for users is whether the dose has been delivered or not. ICOres provides a unique feedback feature that clearly shows when the inhaler has been loaded correctly and is ready for inhalation. This is indicated by a closed window. Upon inhalation the window opens, indicating correct inhalation and confirming that the dose has been delivered. The window stays open until the next dose is loaded. This allows for a caretaker or parent to visually verify that the dose has been delivered.

The feedback feature indication strongly improves compliance and user experience. It also reduces the risk of multiple dosing by users taking an additional dose because they are not sure that the first one has been delivered.

The indications of the feedback feature are: “ready to inhale” and “successful inhalation”.

Humidity protection

ICOres has a tight sealing cover providing a strong barrier against water vapour ingress. Together with a high capacity integrated desiccant, ICOres has a superb humidity protection, guaranteeing a very long in-use time and shelf-time. ICOres does not require any Al-overwrap or additional humidity protection.

Bespoke exterior design

The exterior of ICOres can be designed in many different shapes and colours and it can be customized to meet specific client requirements in terms of:

  • Mouthpiece shape
  • Device shape
  • Colour
  • Material
  • Texture
  • Surface
The design can also be adapted to fit with a special brand, demographic, product family or market segment.